Buy Apriline Dermal Fillers Online USA. Apriline® Fillers are CE- marked injectable gels based on the Hyaluronic Acid developed by scientists with a long track record in Hyaluronic Acid research. Thanks to the advanced one-phase manufacturing process. However, the purity of apriline® Fillers and BDDE rates are well beyond the strict EU requirements. Some dermal fillers have been studied to last close to two years. The three fillers that tend to last the longest are Restylane Lyft, Restylane Defyne, Restylane Refyne, Juvederm, Voluma, Radiesse, and Sculptra. Restylane Defyne is built for balance and used in the nasal labial folds and marionette lines.